Deprescribing antihypertensive treatment in nursing home patients and the effect on blood pressure.

ABSTRACT:

Background

It is debatable whether treating multimorbid nursing home patients with antihypertensive drugs produces beneficial effects. Most cardiovascular guidelines promote treatment; few have advice on how to deprescribe when treatment may no longer be necessary. We investigated the effect of medication review on antihypertensive drug use and the association between cognition, blood pressure, and prescribing.

Methods

From August 2014 to December 2015, 765 patients from 72 units (clusters) in 32 Norwegian nursing homes were included in a 4-month, multicentre, cluster-randomized, controlled trial, with 9-month follow-up. Patients ≥ 65 years old with antihypertensive treatment (n = 295, 39%) were randomized to systematic medication review where the physician received s

SUBMITTER: Gulla C 

PROVIDER: S-EPMC5997621 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature