Ontology highlight
ABSTRACT:
SUBMITTER: Santhakumar H
PROVIDER: S-EPMC5998144 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Santhakumar Hema H Nair Resmi V RV Philips Divya Susan DS Shenoy Sachin J SJ Thekkuveettil Anoopkumar A Ajayaghosh Ayyappanpillai A Jayasree Ramapurath S RS
Scientific reports 20180613 1
Zinc, the essential trace element in human body exists either in the bound or free state, for both structural and functional roles. Insights on Zn<sup>2+</sup> distribution and its dynamics are essential in view of the fact that Zn<sup>2+</sup> dyshomeostasis is a risk factor for epileptic seizures, Alzheimer's disease, depression, etc. Herein, a bipyridine bridged bispyrrole (BP) probe is used for ratiometric imaging and quantification of Zn<sup>2+</sup> in hippocampal slices. The green fluores ...[more]