Long-Term Dose-Response Condensed Tannin Supplementation Does Not Affect Iron Status or Bioavailability.

ABSTRACT: Background: Repeated phytic acid consumption leads to iron absorption adaptation but, to the best of our knowledge, the impact of repeated tannin consumption has not yet been established. Salivary proline-rich proteins (PRPs) may improve iron absorption by precipitating tannins. Objectives: This study aimed to determine the effect of long-term, dose-response condensed tannin supplementation on iron bioavailability and status and to assess the effect of salivary proteins on iron bioavailability during prolonged condensed tannin consumption. A secondary objective was to assess astringency as a potential marker for adaptation to tannins and iron bioavailability. Methods: Eleven nonanemic women were enrolled in a double-blind 3-dose crossover trial. Three (1.5, 0.25, or 0.

SUBMITTER: Delimont NM 

PROVIDER: S-EPMC5998780 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature