A Tutorial in Bayesian Potential Outcomes Mediation Analysis.

ABSTRACT: Statistical mediation analysis is used to investigate intermediate variables in the relation between independent and dependent variables. Causal interpretation of mediation analyses is challenging because randomization of subjects to levels of the independent variable does not rule out the possibility of unmeasured confounders of the mediator to outcome relation. Furthermore, commonly used frequentist methods for mediation analysis compute the probability of the data given the null hypothesis, which is not the probability of a hypothesis given the data as in Bayesian analysis. Under certain assumptions, applying the potential outcomes framework to mediation analysis allows for the computation of causal effects, and statistical mediation in the Bayesian framework gives indirect effects prob

SUBMITTER: Miocevic M 

PROVIDER: S-EPMC5999040 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature