Renal complications of lipodystrophy: A closer look at the natural history of kidney disease.

ABSTRACT: OBJECTIVES:Lipodystrophy syndromes are a group of heterogeneous disorders characterized by adipose tissue loss. Proteinuria is a remarkable finding in previous reports. STUDY DESIGN:In this multicentre study, prospective follow-up data were collected from 103 subjects with non-HIV-associated lipodystrophy registered in the Turkish Lipodystrophy Study Group database to study renal complications in treatment naïve patients with lipodystrophy. METHODS:Main outcome measures included ascertainment of chronic kidney disease (CKD) by studying the level of proteinuria and the estimated glomerular filtration rate (eGFR). Kidney volume was measured. Percutaneous renal biopsies were performed in 9 patients. RESULTS:Seventeen of 37 patients with generalized and 29 of 66 patients with partial lipodystr

SUBMITTER: Akinci B 

PROVIDER: S-EPMC5999575 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature