[BAG family gene and its relationship with lung adenocarcinoma susceptibility].

ABSTRACT:

Background and objective

BAG genes (Bcl-2-associated athanogene) belong to a recently discovered multifunctional anti-apoptosis gene family that regulate various physiological processes which include apoptosis, tumorigenesis, neural differentiation, stress response and cell cycle and so on. The expression status of BAG family genes are related to certain tumor incidence and prognosis. The aim of this study is to explore the association of the BAG family gene expression status with the susceptibility of lung adenocarcinoma.

Methods

The gene expression data of BAG family genes from 29 cases of lung adenocarcinoma tissues and matched pericancerous lung tissues were generated by microarray chips. Cox regression was used to analyze the association between the expression of BAG fa

SUBMITTER: Li Y 

PROVIDER: S-EPMC6000578 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature