Multilevel factors are associated with immunosuppressant nonadherence in heart transplant recipients: The international BRIGHT study.

ABSTRACT: Factors at the level of family/healthcare worker, organization, and system are neglected in medication nonadherence research in heart transplantation (HTx). The 4-continent, 11-country cross-sectional Building Research Initiative Group: Chronic Illness Management and Adherence in Transplantation (BRIGHT) study used multistaged sampling to examine 36 HTx centers, including 36 HTx directors, 100 clinicians, and 1397 patients. Nonadherence to immunosuppressants-defined as any deviation in taking or timing adherence and/or dose reduction-was assessed using the Basel Assessment of Adherence to Immunosuppressive Medications Scale^© (BAASIS^© ) interview. Guided by the Integrative Model of Behavioral Prediction and Bronfenbrenner's ecological model, we analyzed factors at thes

SUBMITTER: Denhaerynck K 

PROVIDER: S-EPMC6001479 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature