Morphologic and Genomic Analyses of New Isolates Reveal a Second Lineage of Cedratviruses.

ABSTRACT: Giant viruses have been isolated and characterized in different environments, expanding our knowledge about the biology of these unique microorganisms. In the last 2 years, a new group was discovered, the cedratviruses, currently composed of only two isolates and members of a putative new family, "Pithoviridae," along with previously known pithoviruses. Here we report the isolation and biological and genomic characterization of two novel cedratviruses isolated from samples collected in France and Brazil. Both viruses were isolated using Acanthamoeba castellanii as a host cell and exhibit ovoid particles with corks at either extremity of the particle. Curiously, the Brazilian cedratvirus is ∼20% smaller and presents a shorter genome of 460,038 bp, coding for fewer proteins than other cedrat

SUBMITTER: Rodrigues RAL 

PROVIDER: S-EPMC6002711 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature