The prognostic and diagnostic value of 18F-FDG PET/CT for assessment of symptomatic osteoarthritis.

ABSTRACT:

Objective

The objective of this study was to assess the clinical significance of increased fluorine-18-fluorodeoxyglucose (F-FDG) uptake on PET/CT in joints for evaluation of symptomatic osteoarthritis (OA) and prediction of progression.

Patients and methods

In this prospective study, shoulder, hip, and knee joints were imaged in 65 patients undergoing routine F-FDG PET/CT imaging. Patients completed the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire to assess joint pain, stiffness, and physical function. Standardized uptake values (SUVs) were measured in hip, knee, acromioclavicular (AC), and glenohumeral (GH) joints. Scout PET/CT images were evaluated for OA using the Kellgren and Lawrence (K/L) system. Patients were followed-up for 5

SUBMITTER: Nguyen BJ 

PROVIDER: S-EPMC6002865 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature