Bispectral index to guide induction of anesthesia: a randomized controlled study.

ABSTRACT:

Background

It is unknown to what extent hypotension frequently observed following administration of propofol for induction of general anesthesia is caused by overdosing propofol. Unlike clinical signs, electroencephalon-based cerebral monitoring allows to detect and quantify an overdose of hypnotics. Therefore, we tested whether the use of an electroencephalon-based cerebral monitoring will cause less hypotension following induction with propofol.

Methods

Subjects were randomly assigned to a bispectral index (BIS)-guided (target range 40-60) or to a weight-related (2 mg.kg^- 1) manual administration of propofol for induction of general anesthesia. The primary endpoint was the incidence of hypotension following the administration of propofol. Secondary endpoints inc

SUBMITTER: Rusch D 

PROVIDER: S-EPMC6003112 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature