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Microorganisms resistant to conventional antimicrobials in acute exacerbations of chronic obstructive pulmonary disease.


ABSTRACT:

Background

Antimicrobial treatment for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) remains controversial. In some cases AECOPD are caused by microorganisms that are resistant to treatments recommended by guidelines. Our aims were: 1) identify the risk factors associated with infection by microorganisms resistant to conventional treatment (MRCT), 2) Compare the clinical characteristics and outcomes of patients with AECOPD resulting from MRCT against those with AECOPD from other causes.

Methods

We prospective analysed a cohort of patients admitted with severe AECOPD (2009 to 2015) who were assigned to three groups: patients with MRCT (those patients with germs resistant to antibiotics recommended in guidelines), patients with microorganisms sensitive

SUBMITTER: Estirado C 

PROVIDER: S-EPMC6003174 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature