Spatial relationship of 2-deoxy-2-[¹⁸F]-fluoro-D-glucose positron emission tomography and magnetic resonance diffusion imaging metrics in cervical cancer.

ABSTRACT:

Background

This study investigated the spatial relationship of 2-deoxy-2-[¹⁸F]-fluoro-D-glucose positron emission tomography ([¹⁸F]FDG-PET) standardized uptake values (SUVs) and apparent diffusion coefficients (ADCs) derived from magnetic resonance (MR) diffusion imaging on a voxel level using simultaneously acquired PET/MR data. We performed an institutional retrospective analysis of patients with newly diagnosed cervical cancer who received a pre-treatment simultaneously acquired [¹⁸F]FDG-PET/MR. Voxel SUV and ADC values, and global tumor metrics including maximum SUV (SUV_max), mean ADC (ADC_mean), and mean tumor-to-muscle ADC ratio (ADC_T/M) were compared. The impacts of histology, grade, and tumor volume on the vox

SUBMITTER: Floberg JM 

PROVIDER: S-EPMC6003894 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature