Structure of the alternative complex III in a supercomplex with cytochrome oxidase.

ABSTRACT: Alternative complex III (ACIII) is a key component of the respiratory and/or photosynthetic electron transport chains of many bacteria^1-3. Like complex III (also known as the bc₁ complex), ACIII catalyses the oxidation of membrane-bound quinol and the reduction of cytochrome c or an equivalent electron carrier. However, the two complexes have no structural similarity^4-7. Although ACIII has eluded structural characterization, several of its subunits are known to be homologous to members of the complex iron-sulfur molybdoenzyme (CISM) superfamily ⁸ , including the proton pump polysulfide reductase^9,10. We isolated the ACIII from Flavobacterium johnsoniae with native lipids using styrene maleic acid copolymer^11-14, both as an i

SUBMITTER: Sun C 

PROVIDER: S-EPMC6004266 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature