Selection of growth-related genes and dominant genotypes in transgenic Yellow River carp Cyprinus carpio L.

ABSTRACT: Transgenic Yellow River carp is characterized by rapid growth rate and high feed-conversion efficiency and exhibits a great application prospect. However, there is still a significant separation of growth traits in the transgenic Yellow River carp family; as such, growth-related genotypes must be screened for molecular marker-assisted selection. In this study, 23 growth-related candidate genes containing 48 SNP markers were screened through bulked segregant analysis (BSA) among transgenic Yellow River carp family members showing significant separation of growth traits. Then, two growth-related genes (Nos. 17 and 14 genes) were identified through combined genome-wide association study (GWAS) of candidate genes and validation of the full-sibling family approach. Nos. 17 and 14 genes encode B

SUBMITTER: Luo L 

PROVIDER: S-EPMC6004361 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature