The Changing Face of Noncardia Gastric Cancer Incidence Among US Non-Hispanic Whites.

ABSTRACT:

Background

The initial step for noncardia gastric carcinogenesis is atrophic gastritis, driven by either Helicobacter pylori infection or autoimmunity. In recent decades, the prevalence rates of these two major causes declined and increased, respectively, with changes in Western lifestyles. We therefore assessed gastric cancer incidence trends for US race/ethnic groups, 1995-2013.

Methods

Age-standardized rates (ASRs) from 45 North American Association of Central Cancer Tumor Registries were summarized by estimated annual percentage change (EAPC) and 95% confidence intervals (CIs). Age period cohort models supplemented standard descriptive techniques and projected future trends.

Results

There were 137 447 noncardia cancers in 4.4 billion person-years of observation. A

SUBMITTER: Anderson WF 

PROVIDER: S-EPMC6005150 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature