Predictors of oral anticoagulant non-prescription in patients with atrial fibrillation and elevated stroke risk.

ABSTRACT:

Background

Many patients with atrial fibrillation (AF) and elevated stroke risk are not prescribed oral anticoagulation (OAC) despite evidence of benefit. Identification of factors associated with OAC non-prescription could lead to improvements in care.

Methods and results

Using NCDR PINNACLE, a United States-based ambulatory cardiology registry, we examined factors associated with OAC non-prescription in patients with non-valvular AF at elevated stroke risk (CHA₂DS₂-VASc ≥2) between January 5, 2008 and December 31, 2014. Among 674,841 patients, 57% were treated with OAC (67% of whom were treated with warfarin). OAC prescription varied widely (28%-75%) across preselected strata of age, stroke risk (CHA₂DS₂-VASc), and bleeding risk

SUBMITTER: Lubitz SA 

PROVIDER: S-EPMC6005198 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature