Antiretroviral therapy interruptions: impact on HIV treatment and transmission.

ABSTRACT:

Introduction

Successful management of pediatric and adult human immunodeficiency virus (HIV) disease includes lifelong administration of antiretroviral therapy (ART). The need for the continuous use of antiretroviral drugs throughout the life course poses a challenge to children, adolescents, and adults living with HIV and their caregivers. Historically, treatment interruptions have been viewed as a negative therapeutic strategy. Recently, however, treatment interruptions or treatment reduction strategies have become a focus of investigations as innovative approaches to the long-term management of HIV disease. Current challenges with treatment interruptions include identifying an appropriate timeframe for length of interruptions and identifying HIV patient populations in whom the t

SUBMITTER: Dubrocq G 

PROVIDER: S-EPMC6005325 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature