Ischemic Mitral Regurgitation: Abnormal Strain Overestimates Nonviable Myocardium.

ABSTRACT:

Background

Therapy for moderate ischemic mitral regurgitation remains unclear. Determination of myocardial viability, a necessary prerequisite for an improvement in regional contractility, is a likely key factor in determining response to revascularization alone. Myocardial strain has been proposed as a viability measure but has not been compared with late gadolinium enhancement (LGE) cardiac magnetic resonance imaging. We hypothesized that abnormal strain overestimates nonviable left ventricular (LV) segments measured with LGE and that ischemia and mechanical tethering by adjacent transmural myocardial infarction (TMI) also decreases strain in viable segments.

Methods

Sixteen patients with mild or greater ischemic mitral regurgitation and 7 healthy volunteers underwent card

SUBMITTER: Morgan AE 

PROVIDER: S-EPMC6005393 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature