Strategies to decrease oxidative stress biomarker levels in human medical conditions: A meta-analysis on 8-iso-prostaglandin F_2α.

ABSTRACT: The widespread detection of elevated oxidative stress levels in many medical conditions has led to numerous efforts to design interventions to reduce its effects. Efforts have been wide-ranging, from dietary changes to administration of antioxidants, supplements, e.g., omega-3-fatty acids, and many medications. However, there is still no systemic assessment of the efficacy of treatments for oxidative stress reduction across a variety of medical conditions. The goal of this meta-analysis is, by combining multiple studies, to quantitate the change in the levels of the popular oxidative stress biomarker 8-iso-prostaglandin F_2α (8-iso-PGF_2α) after a variety of treatment strategies in human populations. Nearly 350 unique publications with 180 distinct strategies were inclu

SUBMITTER: van 't Erve TJ 

PROVIDER: S-EPMC6007822 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature