The association of lifetime alcohol use with mortality and cancer risk in older adults: A cohort study.

ABSTRACT:

Background

While current research is largely consistent as to the harms of heavy drinking in terms of both cancer incidence and mortality, there are disparate messages regarding the safety of light-moderate alcohol consumption, which may confuse public health messages. We aimed to evaluate the association between average lifetime alcohol intakes and risk of both cancer incidence and mortality.

Methods and findings

We report a population-based cohort study using data from 99,654 adults (68.7% female), aged 55-74 years, participating in the U.S. Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial. Cox proportional hazards models assessed the risk of overall and cause-specific mortality, cancer incidence (excluding nonmelanoma skin cancer), and combined risk o

SUBMITTER: Kunzmann AT 

PROVIDER: S-EPMC6007830 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature