Addition of ultrasound to mammography in the case of dense breast tissue: systematic review and meta-analysis.

ABSTRACT:

Background

Mammography is less effective in detecting cancer in dense than in fatty breasts.

Methods

We undertook a systematic search in PubMed to identify studies on women with dense breasts who underwent screening with mammography supplemented with ultrasound. A meta-analysis was undertaken on the proportion of cancers detected only by ultrasound, out of all screen-detected cancers, and the proportion of women with negative mammography who were referred for assessment following ultrasound screening.

Results

Twenty-nine studies satisfied our inclusion criteria. The proportion of total cancers detected only by ultrasound was 0.29 (95% CI: 0.27-0.31), consistent with an approximately 40% increase in the detection of cancers compared to mammography. In the studied popul

SUBMITTER: Rebolj M 

PROVIDER: S-EPMC6008336 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature