Synthesis of pyrazolopyrimidinones using a "one-pot" approach under microwave irradiation.

ABSTRACT: A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established. A variety of substituents was tolerated at the 2 and 5 positions, including functionalized aryls, heterocycles, and alkyl groups.

SUBMITTER: Kelada M 

PROVIDER: S-EPMC6009099 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature