Ontology highlight
ABSTRACT:
SUBMITTER: Liu D
PROVIDER: S-EPMC6009197 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Beilstein journal of organic chemistry 20180522
The system of the hypervalent iodine(III) reagent FPID and (4-MeOC<sub>6</sub>H<sub>4</sub>)<sub>3</sub>P was successfully applied to solid-phase peptide synthesis and cyclic peptide synthesis. Four peptides with biological activities were synthesized through SPPS and the bioactive cyclic heptapeptide pseudostellarin D was obtained via solution-phase peptide synthesis. It is worth noting that FPID can be readily regenerated after the peptide coupling reaction. ...[more]