Effectiveness of amoxicillin alone in the treatment of uncomplicated acute otitis media: a systematic review protocol.

ABSTRACT:

Introduction

Amoxicillin is the first-line antibiotic recommended by most scientific societies for the treatment of uncomplicated acute otitis media (AOM) in children and adults. In low-income and middle-income countries however, absence of setting-specific recommendations and antibiotic resistance, promoted by higher population density and over-the-counter antibiotic availability, could hamper the effectiveness of amoxicillin. We aim to provide updated information to enable evidence-based decisions for first-line therapy of uncomplicated AOM in our setting.

Methods and analysis

We will conduct a systematic review of all randomised controlled trials on the clinical effectiveness of amoxicillin for the treatment of uncomplicated AOM in children above 6 months and adults. The

SUBMITTER: Choffor-Nchinda E 

PROVIDER: S-EPMC6009545 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature