Association of total homocysteine with blood pressure in a general population of Chinese adults: a cross-sectional study in Jiangsu province, China.

ABSTRACT:

Objectives

We aimed to evaluate the relation of total homocysteine (tHcy) concentrations with systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels, and examine the possible modifiers in the association among a general population of Chinese adults.

Design

A cross-sectional study.

Setting

The study was conducted within 21 communities in Lianyungang of Jiangsu province, China.

Participants

A total of 26 648 participants aged ≥35 years and with no antihypertensive drug use were included in the final analysis.

Results

Overall, there was a positive association between tHcy concentrations and SBP (per 5 μmol/L tHcy increase: adjusted β=0.45 mm Hg; 95% CI 0.29 to 0.61) or DBP levels (per 5 μmol/L tHcy increase: adjusted β=0.47 mm Hg; 95% CI 0.

SUBMITTER: Wu H 

PROVIDER: S-EPMC6009617 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature