IL-10(-592A/C) gene variant a predictor of postoperative atrial fibrillation in the north Indian population.

ABSTRACT:

Background

There is an accumulating body of evidence indicating a strong association between inflammation and the pathogenesis of atrial fibrillation (AF) in different ethnicities across the globe. AF increases the risk of stroke and heart failure. Despite various researches on IL-10 response, there is limited clinical evidence present, which demonstrate a role of these immunity regulators in AF. Therefore, this study was designed to decipher the role of IL-10(-592A/C) polymorphism in the development of postoperative AF (post-OP AF).

Method

The study was designed for north Indian patients. The study included 90 patients with AF and 126 controls in sinus rhythm undergoing surgery at Department of Cardiovascular and thoracic surgery, SGPGIMS, Lucknow, India. DNA

SUBMITTER: Yadav S 

PROVIDER: S-EPMC6009777 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature