A novel iris transillumination grading scale allowing flexible assessment with quantitative image analysis and visual matching.

ABSTRACT:

Purpose

To develop a sensitive scale of iris transillumination suitable for clinical and research use, with the capability of either quantitative analysis or visual matching of images.

Methods

Iris transillumination photographic images were used from 70 study subjects with ocular or oculocutaneous albinism. Subjects represented a broad range of ocular pigmentation. A subset of images was subjected to image analysis and ranking by both expert and nonexpert reviewers. Quantitative ordering of images was compared with ordering by visual inspection. Images were binned to establish an 8-point scale. Ranking consistency was evaluated using the Kendall rank correlation coefficient (Kendall's tau). Visual ranking results were assessed using Kendall's coefficient of concordance (Kend

SUBMITTER: Wang C 

PROVIDER: S-EPMC6009845 | biostudies-literature | 2018 Jan-Feb

REPOSITORIES: biostudies-literature