Estimating mean circulatory filling pressure in clinical practice: a systematic review comparing three bedside methods in the critically ill.

ABSTRACT: The bedside hemodynamic assessment of the critically ill remains challenging since blood volume, arterial-venous interaction and compliance are not measured directly. Mean circulatory filling pressure (P_mcf) is the blood pressure throughout the vascular system at zero flow. Animal studies have shown P_mcf provides information on vascular compliance, volume responsiveness and enables the calculation of stressed volume. It is now possible to measure P_mcf at the bedside. We performed a systematic review of the current P_mcf measurement techniques and compared their clinical applicability, precision, accuracy and limitations. A comprehensive search strategy was performed in PubMed, Embase and the Cochrane databases. Studies measuring P_mcf in

SUBMITTER: Wijnberge M 

PROVIDER: S-EPMC6010367 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature