An easy-to-build and re-usable microfluidic system for live-cell imaging.

ABSTRACT:

Background

Real-time monitoring of cellular responses to dynamic changes in their environment or to specific treatments has become central to cell biology. However, when coupled to live-cell imaging, such strategies are difficult to implement with precision and high time resolution, and the simultaneous alteration of multiple parameters is a major challenge. Recently, microfluidics has provided powerful solutions for such analyses, bringing an unprecedented level of control over the conditions and the medium in which cells under microscopic observation are grown. However, such technologies have remained under-exploited, largely as a result of the complexity associated with microfabrication procedures.

Results

In this study, we have developed simple but powerful microfluidic

SUBMITTER: Babic J 

PROVIDER: S-EPMC6011407 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature