Percutaneous direct current stimulation - a new electroceutical solution for severe neurological pain and soft tissue injuries.

ABSTRACT: There is a high medical need to improve the effectiveness of the treatment of pain and traumatic soft tissue injuries. In this context, electrostimulating devices have been used with only sporadic success. There is also much evidence of endogenous electrical signals that play key roles in regulating the development and regeneration of many tissues. Transepithelial potential gradients are one source of the direct current (DC) electrical signals that stimulate and guide the migration of inflammatory cells, epithelial cells, fibroblasts and mesenchymal stem cells to achieve effective wound healing. Up to now, this electrophysiological knowledge has not been adequately translated into a clinical treatment. Here, we present a mobile, handheld electroceutical smart device based on a microcontrol

SUBMITTER: Molsberger A 

PROVIDER: S-EPMC6011884 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature