Spontaneous endometriosis in cynomolgus monkeys as a clinically relevant experimental model.
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ABSTRACT:
SUBMITTER: Nishimoto-Kakiuchi A
PROVIDER: S-EPMC6012197 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Publications
Spontaneous endometriosis in cynomolgus monkeys as a clinically relevant experimental model.
Nishimoto-Kakiuchi A A Netsu S S Okabayashi S S Taniguchi K K Tanimura H H Kato A A Suzuki M M Sankai T T Konno R R
Human reproduction (Oxford, England) 20180701 7
<h4>Study question</h4>Does spontaneous endometriosis in cynomolgus monkeys have the characteristics required of a good experimental model?<h4>Summary answer</h4>Spontaneous endometriosis in cynomolgus monkeys exhibited similar clinicopathological characteristics to the human disease and was useful as an experimental model.<h4>What is known already</h4>The prevalence of endometriosis in autopsied cynomolgus monkeys (Macaca fascicularis) in a breeding colony was reported to be 28.7% in 1993. The ...[more]
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