Metabolic enzymes in glial cells of the honeybee brain and their associations with aging, starvation and food response.

ABSTRACT: The honey bee has been extensively studied as a model for neuronal circuit and memory function and more recently has emerged as an unconventional model in biogerontology. Yet, the detailed knowledge of neuronal processing in the honey bee brain contrasts with the very sparse information available on glial cells. In other systems glial cells are involved in nutritional homeostasis, detoxification, and aging. These glial functions have been linked to metabolic enzymes, such as glutamine synthetase and glycogen phosphorylase. As a step in identifying functional roles and potential differences among honey bee glial types, we examined the spatial distribution of these enzymes and asked if enzyme abundance is associated with aging and other processes essential for survival. Using immunohistochem

SUBMITTER: Shah AK 

PROVIDER: S-EPMC6013123 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature