Efficacy and safety of low-molecular-weight heparin after knee arthroscopy: A meta-analysis.

ABSTRACT:

Background

Venous thromboembolism (VTE) is considered a potentially serious complication of knee arthroscopy and leads to conditions such as deep venous thrombosis (DVT) and pulmonary embolism (PE). Low-molecular-weight heparin (LMWH) is widely employed in knee arthroscopy to reduce perioperative thromboembolic complications. However, the efficacy and safety of LMWH in knee arthroscopy remains unclear.

Methods

Seven randomized controlled clinical trials on LMWH in knee arthroscopy were identified and included in this meta-analysis. The main outcomes of the effectiveness (prevention of DVT and PE) and complications (death, major bleeding, and minor bleeding) of LMWH in knee arthroscopic surgery were assessed using Review Manager 5.3 software.

Results

The meta-analysis

SUBMITTER: Huang HF 

PROVIDER: S-EPMC6013230 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature