Inferior long-term allograft and patient outcomes among recipients of offspring living donor kidneys.

ABSTRACT: While offspring-to-parent living donor kidney transplantations may represent an ideal donor-recipient combination to optimize long-term transplantation outcomes, the sex-specific long-term success of these transplantations remains unclear. We hypothesize that allograft and recipient survivals in offspring-to-parent living donor kidney transplantation differ between men and women due to donor-specific alloimmunization during pregnancy. We retrospectively analyzed long-term allograft and patient survival among men and women who received an offspring living donor kidney compared with those who received other haplotype-matched living donor kidneys. Based on multivariable Cox proportional hazards modeling of Organ Procurement and Transplantation Network data from 2001 to 2015, we found that bot

SUBMITTER: Cohen JB 

PROVIDER: S-EPMC6013327 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature