Raman fingerprints of amyloid structures.

ABSTRACT: Structural differences in pathological and functional amyloid fibrils have been investigated by Raman microspectroscopy. Second-derivative analyses of amide-I and amide-III bands distinguish parallel in-register β-sheets from a β-solenoid. Further, spatially resolved Raman spectra reveal molecular heterogeneity in amyloid structures.

SUBMITTER: Flynn JD 

PROVIDER: S-EPMC6013393 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature