Abnormal brain white matter in patients with right trigeminal neuralgia: a diffusion tensor imaging study.

ABSTRACT:

Background

Idiopathic or classical trigeminal neuralgia (TN) is a chronic painful condition characterized by intermittent pain attacks. Enough evidence demonstrates classical TN is related to neurovascular compression (NVC) at the trigeminal root entry zone (REZ), but white matter change secondary to TN are not totally known.

Methods

Visual Analogue Scale (VAS) and diffusion tensor imaging were performed on 29 patients with right TN and 35 healthy individuals. Voxel-wise analyses were performed with TBSS using multiple diffusion metrics, including fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD). Group differences in these parameters were compared between right TN patients and controls using TBSS and correlations between t

SUBMITTER: Liu J 

PROVIDER: S-EPMC6013416 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature