Association of Hemoglobin A1c and Wound Healing in Diabetic Foot Ulcers.

ABSTRACT: OBJECTIVE:This study evaluated the association between hemoglobin A1c (A1C) and wound outcomes in patients with diabetic foot ulcers (DFUs). RESEARCH DESIGN AND METHODS:We conducted a retrospective analysis of an ongoing prospective, clinic-based study of patients with DFUs treated at an academic institution during a 4.7-year period. Data from 270 participants and 584 wounds were included in the analysis. Cox proportional hazards regression was used to assess the incidence of wound healing at any follow-up time in relation to categories of baseline A1C and the incidence of long-term (≥90 days) wound healing in relation to tertiles of nadir A1C change and mean A1C change from baseline, adjusted for potential confounders. RESULTS:Baseline A1C was not associated with wound healing in univaria

SUBMITTER: Fesseha BK 

PROVIDER: S-EPMC6014539 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature