Symptom Burden of Atrial Fibrillation and Its Relation to Interventions and Outcome in Europe.

ABSTRACT: Little is known about the association of atrial fibrillation symptom burden with quality of life and outcomes. In the Prevention of Thromboembolic Events-European Registry in Atrial Fibrillation (n=6196 patients with atrial fibrillation; mean±SD age, 71.8±10.4 years; 39.7% women), we assessed European Heart Rhythm Association score symptoms and calculated correlations with the standardized health status questionnaire (EQ-5D-5L). Patients were followed up for atrial fibrillation therapies and outcomes (stroke/transient ischemic attack/arterial thromboembolism, coronary events, heart failure, and major bleeding) over 1 year. Most individuals (92%) experienced symptoms. Correlations with health status and quality of life were modest. In multivariable-adjusted regression models, the dichotomiz

SUBMITTER: Schnabel RB 

PROVIDER: S-EPMC6015366 | biostudies-literature | 2018 May

REPOSITORIES: biostudies-literature