Heart failure after the Norwood procedure: An analysis of the Single Ventricle Reconstruction Trial.

ABSTRACT:

Background

Heart failure results in significant morbidity and mortality in young children with hypoplastic left heart syndrome (HLHS) after the Norwood procedure.

Methods

We studied subjects enrolled in the prospective Single Ventricle Reconstruction (SVR) Trial who survived to hospital discharge after a Norwood operation and were followed up to age 6 years. The primary outcome was heart failure, defined as heart transplant listing after Norwood hospitalization, death attributable to heart failure, or symptomatic heart failure (New York Heart Association [NYHA] Class IV). Multivariate modeling was undertaken using Cox regression methodology to determine variables associated with heart failure.

Results

Of the 461 subjects discharged home following a Norwood procedure,

SUBMITTER: Mahle WT 

PROVIDER: S-EPMC6015519 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature