Prior fragility fracture and risk of incident ischaemic cardiovascular events: results from UK Biobank.

ABSTRACT: In the large UK Biobank population-based cohort, we found that amongst men, but not women, prior fragility fracture was associated with increased risk of admission with ischaemic heart disease.

Introduction

We aimed to investigate the relationship between prior fracture and risk of incident ischaemic cardiovascular events in a UK population-based cohort.

Methods

UK Biobank is a large prospective cohort comprising 502,637 men and women aged 40-69 years, with detailed baseline assessment. History of fracture was self-reported, and details of hospital admissions for ischaemic heart disease (IHD) (ICD-10:I20-I25) were obtained through linkage to UK Hospital Episode Statistics. Cox proportional hazards models were used to investigate the prospective relationships between prior fra

SUBMITTER: Paccou J 

PROVIDER: S-EPMC6015763 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature