In Vivo Study on Analgesic, Muscle-Relaxant, Sedative Activity of Extracts of Hypochaeris radicata and In Silico Evaluation of Certain Compounds Present in This Species.

ABSTRACT:

Background

Hypochaeris radicata (flatweed) from the family Asteraceae is a medicinal plant found in Europe, Middle East, and India. In folkloric medication, it is used to heal jaundice, dyspepsia, constipation, rheumatism, and hypoglycemia as well as renal problems. Leaves and roots of the plant have antioxidant and antibacterial properties. The plant is a rich source of pharmacologically active phytochemicals; however, it is explored scantily. The objective of the current study was to identify the chemical composition and investigate the in vivo biological potency of crude extracts of this plant.

Methods

The crude extract and the fractions were screened for various phytochemical groups of constituents following standard procedures. The acute toxicity was assay

SUBMITTER: Abu-Izneid T 

PROVIDER: S-EPMC6016213 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature