Precision Medicine in Targeted Therapies for Severe Asthma: Is There Any Place for "Omics" Technology?

ABSTRACT: According to the current guidelines, severe asthma still represents a controversial topic in terms of definition and management. The introduction of novel biological therapies as a treatment option for severe asthmatic patients paved the way to a personalized approach, which aims at matching the appropriate therapy with the different asthma phenotypes. Traditional asthma phenotypes have been decomposing by an increasing number of asthma subclasses based on functional and physiopathological mechanisms. This is possible thanks to the development and application of different omics technologies. The new asthma classification patterns, particularly concerning severe asthma, include an increasing number of endotypes that have been identified using new omics technologies. The identification of en

SUBMITTER: Galeone C 

PROVIDER: S-EPMC6016214 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature