Obesity, Diabetes, and the Risk of Invasive Group B Streptococcal Disease in Nonpregnant Adults in the United States.

ABSTRACT:

Background

Rates of invasive group B Streptococcus (GBS) disease, obesity, and diabetes have increased in US adults. We hypothesized that obesity would be independently associated with an increased risk of invasive GBS disease.

Methods

We identified adults with invasive GBS disease within Active Bacterial Core surveillance during 2010-2012 and used population estimates from the Behavioral Risk Factor Surveillance System to calculate invasive GBS incidence rates. We estimated relative risks (RRs) of invasive GBS using Poisson analysis with offset denominators, with obesity categorized as class I/II (body mass index [BMI] = 30-39.9 kg/m²) and class III (BMI ≥ 40.0 kg/m²).

Results

In multivariable analysis of 4281 cases, the adjusted RRs of i

SUBMITTER: Pitts SI 

PROVIDER: S-EPMC6016410 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature