The risk of TESE-induced hypogonadism: a systematic review and meta-analysis.

ABSTRACT: BACKGROUND:Testicular sperm extraction (TESE) is a surgical procedure to retrieve spermatozoa from the testes of men with azoospermia to help them achieve biological parenthood. Although effective, the surgical procedure is not without complications and haematoma, devascularization, inflammation and a decrease in testosterone levels have been described as such. The prevalence and duration of hypogonadism and associated symptoms after TESE have not been studied systematically. OBJECTIVE AND RATIONALE:In this systematic review we addressed the following research questions: Are serum testosterone levels decreased after TESE and, if so, do these levels recover over time? What is the prevalence of symptoms and signs related to hypogonadism after TESE and are they related to testosterone levels?

SUBMITTER: Eliveld J 

PROVIDER: S-EPMC6016714 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature