High-resolution μCT of a mouse embryo using a compact laser-driven X-ray betatron source.

ABSTRACT: In the field of X-ray microcomputed tomography (μCT) there is a growing need to reduce acquisition times at high spatial resolution (approximate micrometers) to facilitate in vivo and high-throughput operations. The state of the art represented by synchrotron light sources is not practical for certain applications, and therefore the development of high-brightness laboratory-scale sources is crucial. We present here imaging of a fixed embryonic mouse sample using a compact laser-plasma-based X-ray light source and compare the results to images obtained using a commercial X-ray μCT scanner. The radiation is generated by the betatron motion of electrons inside a dilute and transient plasma, which circumvents the flux limitations imposed by the solid or liquid anodes used in conventional elect

SUBMITTER: Cole JM 

PROVIDER: S-EPMC6016801 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature