Changes in antiepileptic drug-prescribing patterns in pregnant women with epilepsy.

ABSTRACT:

Objective

We analyzed current prescribing patterns for antiepileptic drugs (AEDs) in pregnant women with epilepsy (PWWE) at 20 USA tertiary epilepsy centers.

Methods

The Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study is an NIH-funded, prospective, observational, multicenter investigation of pregnancy outcomes for both mother and child, which enrolled women from December 2012 to January 2016. Inclusion criteria for PWWE included ages 14-45 years and up to 20 weeks gestational age. Exclusion criteria included history of psychogenic nonepileptic spells, expected intelligence quotient (IQ) <70, other major medical illness, progressive cerebral disease, and switching AEDs in pregnancy prior to enrollment.

Results

Three hundred fifty-

SUBMITTER: Meador KJ 

PROVIDER: S-EPMC6016834 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature