Unknown

Dataset Information

0

Bioactive Phenolic and Isocoumarin Glycosides from the Stems of Homalium paniculiflorum.

ABSTRACT: Two new phenolic glycosides (1 and 2) and two new isocoumarin glycosides (3 and 4), along with 14 known compounds (5-18), were isolated from the stems of Homalium paniculiflorum. Their structures were established on the basis of extensive spectroscopic analyses and chemical methods. All new compounds were evaluated for their anti-inflammatory activities via examining the inhibitory activity on nitric oxide (NO) production induced by lipopolysaccharide (LPS) in mouse macrophage RAW 264.7 cells in vitro. Compounds 1 and 4 exhibited inhibitory activities with IC50 values of 30.23 ± 1.23 ?M and 19.36 ± 0.19 ?M, respectively.

SUBMITTER: Wu SY 

PROVIDER: S-EPMC6017599 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Bioactive Phenolic and Isocoumarin Glycosides from the Stems of Homalium paniculiflorum.

Wu Shou-Yuan SY   Fu Yan-Hui YH   Zhou Qi Q   Bai Meng M   Chen Guang-Ying GY   Zhao Si-Yu SY   Han Chang-Ri CR   Song Xiao-Ping XP  

Molecules (Basel, Switzerland) 20180222 2

Two new phenolic glycosides (<b>1</b> and <b>2</b>) and two new isocoumarin glycosides (<b>3</b> and <b>4</b>), along with 14 known compounds (<b>5</b>-<b>18</b>), were isolated from the stems of <i>Homalium paniculiflorum</i>. Their structures were established on the basis of extensive spectroscopic analyses and chemical methods. All new compounds were evaluated for their anti-inflammatory activities via examining the inhibitory activity on nitric oxide (NO) production induced by lipopolysaccha  ...[more]

Similar Datasets

Unknown Four new phenolic glycosides from Baoyuan decoction.
| S-EPMC5343191 | biostudies-literature
Unknown Bioactive Compounds from the Stems of Clausena lansium.
| S-EPMC6149816 | biostudies-other
Unknown Isolation of Bioactive Compounds from Calicotome villosa Stems.
| S-EPMC6017485 | biostudies-literature
Unknown Flavanonol Glycosides from the Stems of Myrsine seguinii and Their Neuroprotective Activities.
| S-EPMC8472518 | biostudies-literature
Unknown Two New Phenolic Constituents from the Stems of Euphorbia griffithii.
| S-EPMC6872693 | biostudies-literature
Unknown Bioactive Diphenyl Ethers and Isocoumarin Derivatives from a Gorgonian-Derived Fungus Phoma sp. (TA07-1).
| S-EPMC5484096 | biostudies-literature
Unknown New Phenylpropanoid and Coumarin Glycosides from the Stems of Hydrangea paniculata Sieb.
| S-EPMC6155810 | biostudies-other
Unknown Phenolic Composition of Grape Stems from Different Spanish Varieties and Vintages.
| S-EPMC8392641 | biostudies-literature
Unknown Bioactive thionic compounds and aromatic glycosides from Ligusticum chuanxiong.
| S-EPMC6147803 | biostudies-other
Unknown Enzymatic Biosynthesis of Simple Phenolic Glycosides as Potential Anti-Melanogenic Antioxidants.
| S-EPMC9312196 | biostudies-literature