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A Novel Colorimetric Fluorescent Probe for SO₂ and Its Application in Living Cells Imaging.

ABSTRACT: A novel chromenylium-based fluorescent probe was exploited for sulphur dioxide (SO₂) detecting. The probe displayed a remarkable fluorescence turn-on response towards SO₂ based on the nucleophilic addition reaction to the carbon-carbon double bond with 105 nm Stock shift. The probe was successfully applied for the quantification of SO₂.The linear detection range was from 0-160 μM with the detection limit as low as 99.27 nM. It also exhibited high selectivity for SO₂ than other reactive species and amino acids. Furthermore, cell staining experiments indicated that the probe was cell membrane permeable and could be used for high-performance imaging of SO₂ in living cells. The superior properties of the probe made it highly promising for use in chemical and biological applications.

SUBMITTER: Wu MY

PROVIDER: S-EPMC6017954 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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A Novel Colorimetric Fluorescent Probe for SO₂ and Its Application in Living Cells Imaging.

Wu Ming-Yu MY Wu Jing J Wang Yue Y Liu Yan-Hong YH Yu Xiao-Qi XQ

Molecules (Basel, Switzerland) 20180410 4

A novel chromenylium-based fluorescent probe was exploited for sulphur dioxide (SO₂) detecting. The probe displayed a remarkable fluorescence turn-on response towards SO₂ based on the nucleophilic addition reaction to the carbon-carbon double bond with 105 nm Stock shift. The probe was successfully applied for the quantification of SO₂.The linear detection range was from 0-160 μM with the detection limit as low as 99.27 nM. It also exhibited high selectivity for SO₂ than other reactive species a ...[more]

PMID: 29642650

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