Controversies about the Secondary Prevention of Spontaneous Preterm Birth.

ABSTRACT: Preterm birth is one of the major global health problems and part of the Millennium Development goals because of the associated high number of perinatal or neonatal mortality and long-term risks of neurodevelopmental and metabolic diseases. Transvaginal sonography has meanwhile been established as a screening tool for spontaneous preterm birth despite its relatively low sensitivity when considering only the cervical length. Vaginal progesterone has been shown to reduce prematurity rates below 34 weeks in a screening population of singleton pregnancies. Up to now, no positive long-term effect could be demonstrated after 2 years. It seems to have no benefit to prolong pregnancies after a period of preterm contractions and in risk patients without cervical shortening. Meta-analyses still demo

SUBMITTER: Kyvernitakis I 

PROVIDER: S-EPMC6018068 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature