Two rsaM Homologues Encode Central Regulatory Elements Modulating Quorum Sensing in Burkholderia thailandensis.

ABSTRACT: The bacterium Burkholderia thailandensis possesses three N-acyl-l-homoserine lactone (AHL) quorum sensing (QS) systems designated BtaI1/BtaR1 (QS-1), BtaI2/BtaR2 (QS-2), and BtaI3/BtaR3 (QS-3). These QS systems are associated with the biosynthesis of N-octanoyl-homoserine lactone (C₈-HSL), N-3-hydroxy-decanoyl-homoserine lactone (3OHC₁₀-HSL), and N-3-hydroxy-octanoyl-homoserine lactone (3OHC₈-HSL), which are produced by the LuxI-type synthases BtaI1, BtaI2, and BtaI3 and modulated by the LuxR-type transcriptional regulators BtaR1, BtaR2, and BtaR3. The btaR1-btaI1 and btaR2-btaI2 gene clusters each carry an additional gene encoding a homologue of the QS repressor RsaM originally identified in the phytopathoge

SUBMITTER: Le Guillouzer S 

PROVIDER: S-EPMC6018367 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature